Answering Your Questions About Inflammation, Cystic Acne, Diabetes, And More


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This episode is brought to you by Rupa Health, Levels, and Pendulum.

Today, as part of my Masterclass series, I’m answering questions submitted by my community through the video app HiHo. I am joined by my good friend and podcast host, Dhru Purohit, to discuss back inflammation, intermittent fasting, treating type 2 diabetes with diet, and much more. Find a link below to follow me on HiHo and we may select your question for a future episode!

Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset.

This episode is brought to you by Rupa Health, Levels, and Pendulum.

Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at

By leveraging biosensors like continuous glucose monitors (CGM), Levels provides real-time feedback on how diet and lifestyle choices impact your metabolic health. Learn more about Levels by going to

Pendulum is the first company to figure out how to harness the amazing benefits of Akkermansia in a probiotic capsule. To receive 20% off your first purchase of Pendulum’s Akkermansia probiotic supplement, go to and use code MARK20.

In this episode, we discuss (audio version / Apple Subscriber version):

  • My recent back injury (4:46 / 1:07)
  • Back inflammation and nerve impingement (10:58 / 7:37)
  • Intermittent fasting (12:08 / 8:45)
  • Treating type 2 diabetes with diet (26:17 / 21:25)
  • Healing cystic acne from the inside out (32:43 / 27:55)
  • Changing the food paradigm (37:57 / 32:49)

Follow me on HiHo here!

Mentioned in this episode:

Calorie Restriction with or without Time-Restricted Eating in Weight Loss

The Carbohydrate-Insulin Model of Obesity: Beyond ‘Calories In, Calories Out’

The Carbohydrate-Insulin Model: a Physiological Perspective on the Obesity Pandemic

Perspective: Obesity—an unexplained epidemic

Food Fix

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