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What is High-Density Lipoprotein (HDL)?
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In this episode we explore the vital role that HDL cholesterol plays in maintaining cardiovascular health. Known as "good cholesterol," HDL helps clear excess fats from the bloodstream, but recent research shows that its role is far more complex than we once thought. We'll discuss how low HDL levels are linked to increased heart disease risk, why simply raising HDL numbers might not be enough, and how lifestyle changes can improve both the quantity and quality of this important molecule. Tune in to learn about the evolving science behind HDL and what it means for your heart health!
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References:
Casula, M., Colpani, O., Xie, S., Catapano, A. L., & Baragetti, A. (2021). HDL in atherosclerotic cardiovascular disease: in search of a role. Cells, 10(8), 1869. https://www.mdpi.com/2073-4409/10/8/1869
Cho, K. H. (2022). The current status of research on high-density lipoproteins (HDL): a paradigm shift from HDL quantity to HDL quality and HDL functionality. International journal of molecular sciences, 23(7), 3967. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999423/
Deng, S., Xu, Y., & Zheng, L. (2022). HDL structure. In HDL Metabolism and Diseases (pp. 1-11). Singapore: Springer Nature Singapore. https://link.springer.com/chapter/10.1007/978-981-19-1592-5_1
Franczyk, B., Rysz, J., Ławiński, J., Rysz-Górzyńska, M., & Gluba-Brzózka, A. (2021). Is a high HDL-cholesterol level always beneficial?. Biomedicines, 9(9), 1083. https://www.mdpi.com/2227-9059/9/9/1083
Koren, M.J. & Helow, W. (Hosts). (2024). Cracking the lipid code. [Podcast Episode]. In MedEvidence! Truth Behind the Data. MedEvidence. https://medevidence.com/cracking-the-lipid-code
Koren, M.J. & Lopez, A. (Hosts). (2023). Two docs talk advanced lipids. [Podcast Episode]. In MedEvidence! Truth Behind the Data. MedEvidence. https://medevidence.com/two-docs-talk-advanced-lipids
National Park Service. (11 March, 2024). Grey wolf. [Website]. U.S. Department of the Interior
Toth, P. P. (2005). The “good cholesterol” high-density lipoprotein. Circulation, 111(5), e89-e91. https://www.ahajournals.org/doi/10.1161/01.CIR.0000154555.07002.CA
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