最高の Legacy Laboratories ポッドキャスト (2024)

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EP 155: Adeno-associated virus as a delivery vector for genetic eye disease treatment, with Paul Wille of Abeona Therapeutics 32:18

3h ago32:18

32:18

0:00 Invitation to our first in-person podcast event 1:30 Intro to The Genetics Podcast 2:20 Welcome to Paul 2:53 Adeno-associated virus (AAV) biology and its advantages over other viral vectors 5:20 The gene therapy landscape and options for therapy development and delivery 6:49 The limitations of working with AAV to deliver gene therapy, includin…

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Hollywood Insider Reveals The Political Divide in America | Roger Simon | ECS EP41 2:07:26

3d ago2:07:26

2:07:26

In this episode of The Ed Clay Show, Ed sits down with Roger L. Simon, an Academy Award-nominated screenwriter, author, and founder of PJ Media. Once a prominent figure within Hollywood’s elite, Simon experienced a profound shift in his political views, leading to his eventual ostracization from the industry. Roger delves into his transition from H…

1
EP 154: Pioneering early disease detection through wearable devices and regular monitoring with Dr. Mike Snyder 41:03

7d ago41:03

41:03

0:00 Introduction 1:00 Overview of Mike’s background and contributions to genomics and preventative medicine, as well as how he first became interested in deep data collection for health monitoring 4:20 The use of various tools, including smartwatches, blood tests, genetic testing, and more, to create a comprehensive view of an individual’s health …

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EP 153: How genomics is re-writing the taxonomy of disease with Lon Cardon, President and CEO of The Jackson Laboratory 40:25

14d ago40:25

40:25

0:00 Intro to The Genetics Podcast 01:00 Welcome to Lon 01:51 Lon’s involvement in the very first GWAS and what drew him to large-scale genomics research 03:32 Was moving away from candidate genes towards GWAS and data sharing initially a controversial idea? 05:25 What Lon believes has driven collaboration and data sharing within research communiti…

1
EP 152: Unlocking the secrets of gene regulation with Nadav Ahituv, Director of the Institute of Human Genetics at UCSF 42:40

21d ago42:40

42:40

01:15 - Introductions 02:02 - How our understanding of the non-coding genome has evolved throughout Nadav’s career 04:56 - Our current understanding of non-coding genome grammar 07:40 - Is there a missing piece to the common variant, common disease paradigm? 10:25 - Introducing ultraconserved elements (UCEs) and human accelerated regions (HARs) 12:…

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"This is How I'm Going to Die" - Jessica Sutta - Pop Star/Vaccine Survivor - ECS EP40 1:27:49

21d ago1:27:49

1:27:49

Jessica Sutta, a former member of the iconic pop group The Pussycat Dolls, opens up about her journey from international pop stardom to becoming a vocal advocate for those impacted by vaccine injuries. Known for her electrifying performances, Jessica experienced a life-altering health crisis after receiving the COVID vaccine. Now, she uses her plat…

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11. The Cycle Ends With Me 51:43

24d ago51:43

51:43

We are joined by Nicole Fernin as we discuss overcoming pain from our past, and breaking the cycle for future generations.Legacy Laboratories による

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EP 151: Understanding cell ageing and its role in disease with Marco Quarta Co-founder and CEO of Rubedo Life Sciences 42:36

28d ago42:36

42:36

0:00 Intro to The Genetics Podcast 01:00 Welcome to Marco 02:00 The areas Marco focused on during his academic career and what motivated him to found his first company 03:18 How our understanding of ageing has changed over the past two decades and some of the current big questions in ageing biology 06:01 How to get a clearer picture of the ageing p…

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From E-Commerce Teen to U.S. President - Nathan Ruff - ECS EP39 1:41:41

1M ago1:41:41

1:41:41

In episode 39 of The Ed Clay Show, Ed sits down with Nathan Ruff, a serial entrepreneur who found early success in E-Commerce at the age of 16 and is now the founder of the One Nine Web Agency. Nathan has set three ambitious life goals: ensuring global access to clean water, achieving a billion-dollar net worth, and running for U.S. president in 20…

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EP 150: Cracking the biological code of aging with Martin Borch Jensen, Co-Founder and Chief Scientific Officer at Gordian Biotechnology 44:21

1M ago44:21

44:21

0:00 Intro to The Genetics Podcast 01:00 Welcome to Martin 01:35 How a particularly large Indian meal resulted in a book about intermittent fasting and the biology of ageing 05:10 The biological mechanisms behind intermittent fasting, and whether it’s been established to extend life expectancy in humans. 10:13 What we know (and what we don’t) about…

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Exposing Child Predators: Alex Rosen’s Mission to Protect Kids - Alex Rosen - ECS EP38 1:37:40

1M ago1:37:40

1:37:40

Alex Rosen, founder of the viral vigilante group Predator Poachers, is on a mission to expose and capture online child predators across the United States. Starting his work at just 19, Alex has orchestrated the arrest of predators in 46 states, leading to over 200 arrests and 40 convictions. His work has brought to light the dark underworld of onli…

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10. Seeing The Best In People 44:15

1M ago44:15

44:15

We are joined by Victor Velasco as we discuss the day in the life of a bounty hunter. We talk about what it takes to see the best in people, even in the worst of circumstances.Legacy Laboratories による

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EP 149: Sequencing 33 million samples to support the UK’s COVID-19 response with Tony Cox, CEO of UK Biocentre 34:16

1M ago34:16

34:16

0:00 Intro to The Genetics Podcast 01:00 Welcome to Tony 02:00 What Tony was expecting going into the role of CEO at UK Biocentre, and how the COVID-19 pandemic changed his plans 03:38 Receiving a phone call from the UK government in March 2020 asking the UK Biocentre to stop all of its projects and focus on sequencing COVID-19 samples 05:12 The UK…

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The DJ Who Changed Music Forever - Rapper/Record Producer DJ Paul - ECS EP37 1:48:11

1M ago1:48:11

1:48:11

DJ Paul, a founding member of the legendary hip-hop group Three 6 Mafia, is a Grammy and Oscar-winning producer, rapper, and DJ. Known for his groundbreaking work in shaping the sound of Southern hip-hop, DJ Paul has left an undeniable mark on the music industry, influencing genres far beyond the South. In this episode of The Ed Clay Show, Ed Clay …

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EP 148: Advancing veteran health through the Million Veteran Program with Dr. Mike Gaziano, professor of medicine at Harvard Medical School 35:13

2M ago35:13

35:13

0:00 Intro 2:00 Mike’s career prior to the Million Veteran Program (MVP), how Mike got to work on MVP, and important milestones in the project's evolution 8:30 Future goals for the Million Veteran Program in expanding and diversifying the research cohort 11:00 The roles of various omics in advancing the project's development 14:30 The most meaningf…

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The Science of Life Transformation: Change Your Mind & Body Forever - Kris Gethin - ECS EP36 1:54:34

2M ago1:54:34

1:54:34

Kris Gethin is a professional bodybuilder, trainer, and entrepreneur. He is the founder of Gethin Gyms and Unmatched Supplements, author of 6 books, and his transformation programs have helped over 150 million people worldwide. On Episode 36 of The Ed Clay Show Ed sits down with Fitness & Lifestyle Coach Kris Gethin. Over the years Kris has been a …

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EP 147: From research to delivering precision medicine in the clinic with Scott Weiss, Professor of Medicine at Harvard University 37:19

2M ago37:19

37:19

0:00 Intro to The Genetics Podcast 01:00 Welcome to Scott 01:55 Scott’s career highlights to date, ranging from epidemiology to the genetics of asthma and chronic obstructive pulmonary disease (COPD) 04:56 How and why Scott decided to transition into genetics 06:30 The advances in our understanding of the genetics of asthma and COPD over the past 2…

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EP 146: The biology of aging with Austin Argentieri, Research Fellow at Harvard Medical School, Affiliate Member of the Broad Institute, and Research Fellow at Massachusetts General Hospital 43:05

2M ago43:05

43:05

0:00 Intro to The Genetics Podcast 01:00 Welcome to Austin 01:42 What is aging and how should we think about it? 03:50 Discussion of Austin’s recent breakthrough paper on aging, including the questions he set out to answer, and the outcomes of the research 06:32 How Austin’s work focuses on using large-scale population proteomics data to create acc…

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Sold His Company for $50 Million, Now He's Changing Messaging with Blockchain - Shane Mac - ECS EP35 2:07:05

2M ago2:07:05

2:07:05

Shane Mac is a Tech Founder & Entrepreneur with a successful track record tackling some of the biggest problems we face with tech in the 21st century. Shane is currently the CEO and Co-Founder of Ephemera, a company developing XMTP and changing the way we communicate using the blockchain and decentralization. Prior to Shane's current venture he co-…

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EP 145: Navigating rare disease drug development regulations with Daniel O’Connor 39:12

2M ago39:12

39:12

0:00 Intro to The Genetics Podcast 01:00 Welcome to Daniel 02:04 Defining rare disease in the age of personalized medicine 04:57 Key touchpoints with the Medicines and Healthcare products Regulatory Agency (MHRA) when developing a new medicine 09:27 Improvements over the course of Daniel’s career when it comes to incentivizing and making the path t…

1
9. It's Time To Turn The Page 29:08

2M ago29:08

29:08

Learn to take the most painful things in your life, overcome them, and use them to help others overcome.Legacy Laboratories による

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Tori Trades Spills Secrets to Winning the Market - Futures Trader Victoria Duke - ECS EP34 1:26:52

2M ago1:26:52

1:26:52

Victoria Duke, known as Tori Trades to her more than half a million followers, is a futures trader who has been trading the market for 9 years. She has amassed a following of over half million people on her YouTube, Instagram, and Twitter profiles where she teaches others the techniques, tricks, and psychology behind futures trading. Victoria learn…

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EP 144: Research Roundup with Dr. Veera: breakthroughs in developmental disorders, Parkinson's, SLE, and Alzheimer's 56:48

3M ago56:48

56:48

0:00 Introduction 1:40 A recurrent de novo mutation in a noncoding region of a small nucleolar RNA gene that has been identified as one of the most common causes of neurodevelopmental disorders This pathogenic variant escaped notice for years because it was not located in a protein coding region of the genome It now shows potential as a target for …

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Bestselling Author Stephen Mansfield - The Dangers of Marxism and How Faith Can Lead a Nation 1:02:36

3M ago1:02:36

1:02:36

Stephen Mansfield is a NYT Bestselling Author with over 30 books under his name. He has written on topics such as religion, history, manhood, politics, and more. Stephen was a pastor at Belmont Church in Nashville, TN for 22 years before launching his career as an author in 2002 when he wrote "The Character and Greatness of Winston Churchill". He f…

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EP 143: Harnessing human data in drug development with Jakob Steinfeldt, Co-Founder and Chief Scientific Officer at Pheiron 36:17

3M ago36:17

36:17

0:00 Intro to The Genetics Podcast 01:00 Welcome to Jakob and background on Pheiron 02:14 What made Jakob decide to start Pheiron, what the company does, and how his scientific background inspired him to found a start-up 5:24 Jakob’s excitement and inspiration around the power and potential of machine learning 07:07 Cardiology and heart failure as …

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Richie Walls - Emmy Award Winning Producer, Behind the Scenes in Hollywood, Movie Magic - ECS EP32 1:43:36

3M ago1:43:36

1:43:36

Richie Walls is an Emmy Award Winning TV/Film Producer who has worked with James Cameron, Johnny Depp, Chris Hemsworth, Burt Reynolds and some more of Hollywood's biggest stars. He's worked with talent agencies, modeling agencies, production companies, and recently launched Nashville's newest production agency Seen Entertainment. Most people aren't…

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EP 142: From genome to bedside: How genetics is transforming modern medical practice with Dr. Andrea Gropman 42:45

3M ago42:45

42:45

0:00 Introduction 1:40 Andrea’s background and how she got into the field of genetics, neuroimaging, and metabolic disorders 4:00 Insights into Andrea’s clinical practice, including the diverse families and patients she serves and her approach to clinical decision-making 6:30 How genetics and genomics have changed the diagnostic journey in the last…

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8. Every Young Person Deserves A Home 48:58

3M ago48:58

48:58

We are joined by Michelle Moses as we discuss the hundreds of thousands of youth in foster care, and what we can do to be part of the solution. Get involved: Coins For College: www.coinsforcollege.org Pathway Family Services: https://pfsffa.org/Legacy Laboratories による

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WLPWR - Secrets to Making Award Winning Records, In the Studio with Eminem & Yelawolf - ECS Ep. 31 1:18:45

3M ago1:18:45

1:18:45

WLPWR is an award-winning music producer who's worked with the likes of Eminem, Yelawolf, Wiz Khalifa, Tech N9ne, The Game, and more... WLPWR's resume includes 3 platinum and 3 gold records, a huge accomplishment for anyone in or around the music studio. - What are some characteristics a music producer looks for in an up and coming artist? - What a…

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EP 141: Bringing genomics to the clinic with Lori Orlando, Associate Prof at Duke University 43:24

3M ago43:24

43:24

0:00 Intro to The Genetics Podcast 01:00 Welcome to Lori Orlando 03:00 Lori’s career: From mathematical modelling to genetics and family history 05:11 The study that revealed 20% of the general population is at a higher risk of disease than average and needs preventative care 07:36 The first five diseases that Lori started analysing through informa…

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Beaver Fleming - World's First Double Backflip, Pro Skater, Nitro Circus - The Ed Clay Show Ep. 30 1:26:20

3M ago1:26:20

1:26:20

Welcome Pro Skater Beaver Fleming to The Ed Clay Show for our 30th Episode! Beaver Fleming is Professional Skateboarder who has made a name for himself through his ingenuity and creativity on a skateboard. He was the first person in the world to pull off a double backflip on a skateboard, invented the "Fleming Flip", and has been a trailblazer in t…

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7. Dealing With Shame 25:57

4M ago25:57

25:57

Shame will steal from your relationships, your future, and the impact you're meant to have on the world. Don't let it.Legacy Laboratories による

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EP 140: The future of Electronic Health Records and data analysis with Ben Goldacre 52:51

4M ago52:51

52:51

0:00 Intro to The Genetics Podcast 1:00 Welcome to Ben Goldacre 02:22 Ben’s open data projects at the Bennett Institute and the challenges they aim to tackle 04:03 Using Electronic Health Records (EHR) to help the National Health Service improve care 06:18 The importance of software development within healthcare data and how to manage salary scales…

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Dallas Alexander - World's Longest Sniper Shot, Canadian Special Forces - The Ed Clay Show Ep. 29 1:52:15

4M ago1:52:15

1:52:15

Dallas Alexander is a former Canadian Joint Task Force 2 (JTF2) Sniper who's team holds the record for the world's longest sniper kill at 2.2 miles. The Joint Task Force 2 (JTF2) is a elite special operations unit of the Canadian Armed Forces who specialize in counter-terrorism operations. Dallas was forced out of his special forces unit after decl…

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EP 139: Rare disease breakthroughs using tRNA with Michelle Werner, CEO of Alltrna and CEO-Partner of Flagship Pioneering 44:42

4M ago44:42

44:42

0:00 Intro to The Genetics Podcast. 01:00 Welcome to Michelle. 02:00 Sstop codon diseases and how are they characterised 03:45 Diseases caused by premature stop codons in haploinsufficient genes. 04:35 The role of transfer RNA technology in finding solutions for premature stop codon diseases. 06:16 How Alltrna is engineering tRNAs which can bind to…

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Logan Misuraca - NASCAR Dreams, Motorsports Racing, Women in Sports - The Ed Clay Show Ep 28 1:07:26

4M ago1:07:26

1:07:26

Logan Misuraca is a racecar driver competing in the NASCAR ARCA Menards Track Series. She started racing when she was 4 years old following in the footsteps of her father and has claimed her spot as one of the few motorsports racers worldwide who are female. Ed and Logan take a deep dive into the world of motorsports as she lays out some of the bar…

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6. How To Show Up When The World Seems To Be Falling Apart 21:59

4M ago21:59

21:59

When the world around you appears to be falling apart, be someone who steps up and turns on the lights.Legacy Laboratories による

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Scott Payne - Undercover FBI Agent, Outlaws, & Neo-Nazis - The Ed Clay Show Ep. 27 2:24:51

4M ago2:24:51

2:24:51

Scott Payne is a retired FBI Special Agent who spent twenty-eight years in law enforcement investigating cases against drug trafficking organizations, human traffickers, outlaw motorcycle clubs, gangs, public corruption, and domestic terrorists. He spent long periods of his career in undercover operations including cases such as violent crime, moto…

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EP 138: Personalised medicine using microbiome models with Dr. Almut Heinken 40:22

4M ago40:22

40:22

0:00 Introduction 1:45 Almut’s research experience, including two recent publications on genome-scale metabolic reconstruction human microorganisms Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine APOLLO: A genome-scale metabolic reconstruction resource of 247,092 diverse human microbes spanning multiple…

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Dr. Michael Liebman - The Scientific Mind- The Ed Clay Show Ep. 26 1:36:24

4M ago1:36:24

1:36:24

Dr. Michael Liebman sits on the scientific advisory board of The Translational and Advanced Medical Center (TAM Center) which is the home of the Cellular Performance Institute (CPI Stem Cells) . He holds a PhD in theoretical chemistry and protein crystallography. He is the Managing Director of IPQ Analytics, LLC and of Strategic Medicine, Inc, and …

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EP 137: Mavis Machirori on promoting equity, diversity, and social justice in genomics research 41:40

4M ago41:40

41:40

0:00 Intro 1:30 Mavis’ career arc, from starting as a midwife to researching medical innovation and technology with an emphasis on advocacy and equity 7:00 Systemic issues that are easily overlooked in medical research and advancements Webinar: Participant Diversity: Increasing the Impact of Biomedical Research Webinar 10:00 Addressing Eurocentrici…

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Struggle Jennings - Redemption Through Music - The Ed Clay Show Ep. 25 2:11:07

5M ago2:11:07

2:11:07

Struggle Jennings is a Rapper & Songwriter from Nashville, TN. Struggle is the grandson of Waylon Jennings, was one of the original members of Yelawolfs Slumerican label, and now is the owner of his very own Angels and Outlaws Record Label. Struggle's music is at the heart of the intersection between country and rap. Struggle released his first stu…