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TWiP 241: There once was a patient from China
Manage episode 435130702 series 76477
コンテンツは Vincent Racaniello によって提供されます。エピソード、グラフィック、ポッドキャストの説明を含むすべてのポッドキャスト コンテンツは、Vincent Racaniello またはそのポッドキャスト プラットフォーム パートナーによって直接アップロードされ、提供されます。誰かがあなたの著作物をあなたの許可なく使用していると思われる場合は、ここで概説されているプロセスに従うことができますhttps://ja.player.fm/legal。
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251 つのエピソード
Manage episode 435130702 series 76477
コンテンツは Vincent Racaniello によって提供されます。エピソード、グラフィック、ポッドキャストの説明を含むすべてのポッドキャスト コンテンツは、Vincent Racaniello またはそのポッドキャスト プラットフォーム パートナーによって直接アップロードされ、提供されます。誰かがあなたの著作物をあなたの許可なく使用していると思われる場合は、ここで概説されているプロセスに従うことができますhttps://ja.player.fm/legal。
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251 つのエピソード
すべてのエピソード
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This Week in Parasitism
TWiP solves the case of the woman who went to Belize and notices a lesion on her face, and presents a new clinical case for you to solve. Hosts: Vincent Racaniello , Daniel Griffin , and Christina Naula Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Links for this episode Join the MicrobeTV Discord server Letters read on TWiP 251 New Case Recent case, Arusha hospital, 1800 m, 28 yo comes in, has been visiting game parks. Developing fevers, malaise, bad headaches, body aches, somnolent. Blood smears negative, no malaria. Repeat blood smear, see something extra-erythrocytic. This gives them the diagnosis. HIV neg, no toxic habits, no history. Symptom onset about a week ago. Rest of family is ok. Become a patron of TWiP Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees…
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This Week in Parasitism
1 TWiP 250: Gut bacteria help Trichinella suppress colitis 51:46
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51:46TWiP reviews a study showing that the gut microbiota is essential for suppression of colitis by Trichinella spiralis . Hosts: Vincent Racaniello , Daniel Griffin , and Christina Naula Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Links for this episode Join the MicrobeTV Discord server Gut bacteria and Trichinella suppression of colitis (PLoS NTD) Become a patron of TWiP Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees…
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This Week in Parasitism
TWiP solves the case of the middle-aged man with eosinophilia and a history of sexual activity with paid sex workers in Okinawa, and presents a new case for you to solve. Hosts: Vincent Racaniello , Daniel Griffin , and Christina Naula Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Links for this episode Join the MicrobeTV Discord server Letters read on TWiP 249 New Case Woman in 30s or 40s goes to Belize and after returning notices a lesion on her face. She goes to see several physicians and despite a number of topical creams the ulcer on her face does not heal. She is then referred to our office where a certain parasitic infection is considered and we involve our friends at Columbia to help us with the diagnosis.. Become a patron of TWiP Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees…
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This Week in Parasitism
1 TWiP 248: Toxoplasma reduces Alzheimer's disease 1:06:59
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1:06:59TWiP reviews the observation that infection of Azlheimer’s disease mice with Toxoplasma gondii reduces brain amyloid density globally and regionally. Hosts: Vincent Racaniello , Dickson Despommier , Daniel Griffin , and Christina Naula Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Links for this episode Join the MicrobeTV Discord server Toxoplasma reduces amyloid in brain (J Inf Dis) Hero: Theodor Hiepe (Parasitol Res) Become a patron of TWiP Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees…
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This Week in Parasitism
TWiP solves the case of the Manhattan man with pain on urination or ejaculation, and presents a new case for you to solve. Hosts: Vincent Racaniello , Dickson Despommier , Daniel Griffin , and Christina Naula Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Links for this episode Join the MicrobeTV Discord server Hero: Charles Louis Alphonse Laveran Letters read on TWiP 247 New Case A middle-aged male is referred to evaluation because of eosinophilia. This man is married, living here in the NY tristate area, and this was picked up on ‘routine blood work’ by his primary care doctor. This man had been in the military, serving as a marine, with time spent in Okinawa, Japan. This individual does report sexual activity with paid sex workers while in Okinawa but has been monogamous with his current wife for many years. A number of investigations are done with a test coming back showing serological evidence of a prior parasitic infection and he was treated with an antiparasitic medicine with resolution of the eosinophilia. The eosinophilia returned and he was referred to us. Blood work is now down showing evidence of a viral infection that might explain why the eosinophilia returned after treatment. Pt is HIV negative. This was prior to the COVID-19 pandemic. He is on no medications and in general feels fine. Become a patron of TWiP Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees…
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This Week in Parasitism
1 TWiP 246: Everything spiral: a worm in a hurry 1:23:52
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1:23:52TWiP taps into Dickson’s knowledge of Trichinella to discuss an outbreak in humans who consumed rare bear meat, and the impact of globalization and climate change on the epidemiology of the species. Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Links for this episode Join the MicrobeTV Discord server Outbreak of human trichinellosis (CCDR) Impact of climate change on Trichinella (Food Waterborne Parasit) Letters read on TWiP 246 Become a patron of TWiP Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees…
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This Week in Parasitism
1 TWiP 245: Flying purple people eater with Ben LaBrot 1:16:22
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1:16:22Founder of Floating Doctors Ben LaBrot joins TWiP to solve the case of the 1 year old in northeastern Panama with a fatal leg infection, followed by a discussion of the history and mission of Floating Doctors. Hosts: Vincent Racaniello , Daniel Griffin , and Christina Naula Guest: Ben LaBrot Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Links for this episode Join the MicrobeTV Discord server Floating Doctors Letters read on TWiP 245 New Case A man in his early 20s comes in reporting pain when he urinates or ejaculates. He reports that he is sexually active. He does confide that he has been in a relationship with a woman but he had a sexual encounter outside this relationship about 2 weeks ago when they were on a break and he did not wear protection. He feels like he needs to urinate more often and describes thin white discharge from the penis. He reports that he has no history of any sexually transmitted infections and had no medical issues prior to this. Become a patron of TWiP Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees…
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This Week in Parasitism
Lilach Sheiner joins TWiP to talk about her career and her work on engineering Toxoplasma gondii secretion systems for intracellular delivery of multiple large therapeutic proteins to neurons. Hosts: Vincent Racaniello , Dickson Despommier , and Christina Naula Guest: Lilach Sheiner Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Links for this episode Join the MicrobeTV Discord server Engineering T. gondii for protein secretion (Nat Micro) Become a patron of TWiP Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees…
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This Week in Parasitism
TWiP solves the case of the Woman with White Worms, and submits a new case involving a 1 year old in northeastern Panama with a fatal leg infection. Hosts: Vincent Racaniello , Dickson Despommier , Daniel Griffin , and Christina Naula Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Links for this episode Join the MicrobeTV Discord server Enterobius, the pinworm ( TWiP 19 ) Hero: Mary Pritchard New Case This case comes from Panama mid summer 2024. A provider for Floating Doctors working in the coastal region in northeastern Panama. This case involves a one year old, so the history is a bit difficult, but there may have initially been a scratch or some sort of break in the skin. Otherwise healthy but over a period of time this area expands and becomes a deep necrotic wound on the leg. Several other nearby wounds develop and become deep and infected. By the time this one year old is seen by the provider much of the leg appears eaten away. This is just the tip of the iceberg as a number of others develop similar wounds in the area. No prior medical history. Become a patron of TWiP Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees…
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This Week in Parasitism
TWiP reviews a study showing that intestinal helminth infection impairs vaccine-induced T cell responses through an IL-10 pathway, which compromised protection against antigenically drifted SARS-CoV-2 variants. Hosts: Vincent Racaniello , Daniel Griffin and Christina Naula Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Links for this episode Join the MicrobeTV Discord server Worms impair COVID vaccines (Sci Trans Med) Heligmosomoides image (Wiki Commons) Become a patron of TWiP Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees…
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This Week in Parasitism
1 TWiP 241: There once was a patient from China 1:14:57
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1:14:57T
This Week in Parasitism
1 TWiP 240: A daily history of malaria with Sean Murphy 57:17
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57:17Sean Murphy joins TWiP to discuss his career and the work of his laboratory to assess the daily natural history of asymptomatic Plasmodium infections in adults and older children in Katakwi, Uganda. Hosts: Vincent Racaniello , Dickson Despommier and Christina Naula Guest: Sean Murphy Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Links for this episode Join the MicrobeTV Discord server Daily natural history of Plasmodium infections (Lancet Microbe) Become a patron of TWiP Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees…
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This Week in Parasitism
1 TWiP 239: Cryptosporidiosis from NYC tap water in an AIDS patient 30:49
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30:49TWiP solves the case of the AIDS patient who developed fever and watery diarrhea after drinking NYC tap water, and present a new case for your sleuthing. Hosts: Vincent Racaniello and Daniel Griffin Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Links for this episode Join the MicrobeTV Discord server Cryptosporidium ( TWiP 18 ) Letters read on TWiP 239 Become a patron of TWiP New Case Man in his 70s originally from Mainland China, then Hong Kong who has been living in the US for decades is admitted to the hospital with fever for 6 days. He reports that he saw his primary care physician in Queens and was referred to the hospital after blood work revealed a sodium level of 123 and an increased monocyte count. Pt reports drenching sweats, lots of outdoor activity walking in local parks in Queens. He reports he does not feel particularly sick. PMH-HTN, BPH PSH-neg Social-retired, no wife, has one son, no pets, no exotic exposures or recent travel VS febrile to 39.5, tachycardia, meets sepsis criteria PE -unremarkable Labs, nl wbc, eos-0, elevated neutrophils and monocytes, Na-123, elevated AST, elevated ALT, low platelets, low Hct, CT Chest A/P unremarkable Send your guesses to twip@microbe.tv with TWiP 239 in the subject line Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees…
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This Week in Parasitism
Michael Barrett joins TWiP to discuss progress in the elimination of human African trypanosomiasis caused by Trypanosoma brucei gambiense . Hosts: Daniel Griffin , Dickson Despommier and Christina Naula Guest: Michael Barrett Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Links for this episode Join the MicrobeTV Discord server Elimination of human African trypanosomiasis (PLoS NTD) Hero: David Livingstone Become a patron of TWiP Send your guesses to twip@microbe.tv with TWiP 237 in the subject line Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees…
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This Week in Parasitism
1 TWiP 237: Pass the venison, deer with Marilyn Fabbri 57:01
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57:01Marilyn Fabbri joins TWiP to reveal the case of a patient who became very ill after he and a number of friends attended a large dinner where venison and boar were served. Hosts: Daniel Griffin , Dickson Despommier and Christina Naula Guest: Marilyn Fabbri Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Links for this episode Join the MicrobeTV Discord server Toxoplasma gondii ( TWiP 12 ) Parasitic Diseases Lectures #15: Toxoplasmosis Letters read on TWiP 237 Become a patron of TWiP New Case Man in his 60s with HIV/AIDS CD4 count less than 50, CD4% less than 5% and elevated viral load (VL) with report of prior CNS toxoplasmosis requiring a craniotomy, disseminated Mycobacterium avium complex (MAC), comes in with fever and very watery diarrhea x 4 days. He reports that he lives in Georgia but comes up to NY for his HIV care and stays in NYC. Send your guesses to twip@microbe.tv with TWiP 237 in the subject line Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees…
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