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Decoding Aging and the Environment with Cornelia van Duijn
Manage episode 449874171 series 3396598
コンテンツは Dale Yuzuki and Olink Proteomics によって提供されます。エピソード、グラフィック、ポッドキャストの説明を含むすべてのポッドキャスト コンテンツは、Dale Yuzuki and Olink Proteomics またはそのポッドキャスト プラットフォーム パートナーによって直接アップロードされ、提供されます。誰かがあなたの著作物をあなたの許可なく使用していると思われる場合は、ここで概説されているプロセスに従うことができますhttps://ja.player.fm/legal。
Welcome to the Olink® Proteomics in Proximity podcast!
Below are some useful resources mentioned in this episode:
Olink tools and software
Olink® Explore 3072, the platform utilized by the UK Biobank to measure ~3000 proteins in plasma: https://olink.com/products-services/explore/
Olink® Explore HT, Olink’s most advanced solution for high-throughput biomarker discovery, measuring 5400+ proteins simultaneously with a streamlined workflow and industry-leading specificity: https://olink.com/products-services/exploreht/
UK Biobank Pharma Proteomics Project (UKB-PPP), one of the world’s largest scientific studies of blood protein biomarkers conducted to date, https://www.ukbiobank.ac.uk/learn-more-about-uk-biobank/news/uk-biobank-launches-one-of-the-largest-scientific-studies
Research articles
The support of human genetic evidence for approved drug indications
Matthew R Nelson et al, Nature Genetics 2015
https://www.nature.com/articles/ng.3314
Proteomic aging clock predicts mortality and risk of common age-related diseases in diverse populations
M. Austin Argentieri et al, Nature Medicine 2024
https://www.nature.com/articles/s41591-024-03164-7
Plasma protein-based organ-specific aging and mortality models unveil diseases as accelerated aging of organismal systems
Ludger J.E. Goeminne et al, Cell Metabolism 2024, in press
https://www.sciencedirect.com/science/article/abs/pii/S1550413124004017?via%3Dihub
Plasma proteomic associations with genetics and health in the UK Biobank
Benjamin B. Sun et, Nature 2023
https://www.nature.com/articles/s41586-023-06592-6
Rare variant associations with plasma protein levels in the UK Biobank
Ryan S. Dhindsa; Nature 2023
https://www.nature.com/articles/s41586-023-06547-x
Disease prediction with multi-omics and biomarkers empowers case–control genetic discoveries in the UK Biobank
Manik Garg, Nature Genetics, 2024
https://www.nature.com/articles/s41588-024-01898-1
China Kadoorie Biobank: https://www.ckbiobank.org/publications
Publications: https://www.ckbiobank.org/publications
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