Luke Hughes, PhD

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In this episode Luke Hughes, PhD aka the Drake of BFR returns to discuss his recent paper titled "Aerobic exercise with blood flow restriction causes local and systemic hypoalgesia and increases circulating opioid and endocannabinoid levels". This study followed similar methods to his previous work in terms of outcome measures and its general design. Give it a listen and let us know what you think. Papers referenced during the podcast below: Hughes, L., Grant, I., & Patterson, S. D. (n.d.). Aerobic exercise with blood flow restriction causes local and systemic hypoalgesia 2 and increases circulating opioid and endocannabinoid levels. Hughes, L., & Patterson, S. D. (2020). The effect of blood flow restriction exercise on exercise-induced hypoalgesia and endogenous opioid and endocannabinoid mechanisms of pain modulation. Journal of Applied Physiology. https://doi.org/10.1152/japplphysiol.00768.2019 Song, J. S., Spitz, R. W., Yamada, Y., Bell, Z. W., Wong, V., Abe, T., & Loenneke, J. P. (2021). Exercise-induced hypoalgesia and pain reduction following blood flow restriction: a brief review. Physical Therapy in Sport: Official Journal of the Association of Chartered Physiotherapists in Sports Medicine. https://doi.org/10.1016/j.ptsp.2021.04.005 Slysz, J. T., & Burr, J. F. (2021). Ischemic Preconditioning: Modulating Pain Sensitivity and Exercise Performance. Frontiers in Physiology, 12, 944. Fraessdorf, J., Hollmann, M. W., Hanschmann, I., Heinen, A., Weber, N. C., Preckel, B., & Huhn, R. (2015). Role of Endogenous Opioid System in Ischemic-Induced Late Preconditioning. PloS One, 10(7), e0134283. Intro music: Trick or Treat (instrumental) by RYYZN https://soundcloud.com/ryyzn Creative Commons — Attribution 3.0 Unported — CC BY 3.0 Free Download / Stream: https://bit.ly/l_trick-or-treat Music promoted by Audio Library https://youtu.be/uNPXJ9CDzbc

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