We are awash with information on exercise, and a lot of it is not science-based. Additionally, various topics including quantum mechanics, LEAN Six Sigma, and mental health can inform our application of exercise. Endnotes is a walk through the various topics supporting exercise prescription. Hormesys exists to educate on the application of precision-based exercise programming using Blood Flow Restriction (BFR), point-of-care lactate testing, remote therapeutic monitoring (RTM), molecular exercise physiology, dosing exercise for mental health, and other interventions.