最高の Preprints In Motion ポッドキャスト (2024)

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Surviving freezing through leg amputation. But be careful about regeneration! 55:42

10M ago55:42

55:42

Episode 45 - Surviving freezing through leg amputation. But be careful about regeneration! This week we discussed how flies survive in freezing temperatures with Anne Sustar, a Research Scientist / Lab Manager, Dominic Golding, a medical student, and John Tuthill (@casa_tuthill), Associate professor at the University of Washington, Seattle. Read th…

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Holiday special with Jonny Coates 49:57

11M ago49:57

49:57

This week we celebrate the end of the year by chatting with our host Jonny Coates (@JACoates), Associate Director at ASAPBio. Join us for a conversation on the importance of all things preprints, science communication, open access, career development, and community building, plus his decision to leave academia and how this podcast started! If you s…

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Review Commons: One review to rule them all 51:34

1y ago51:34

51:34

It's open access week 2023 and to celebrate we focus on preprint peer review with Review Commons. We talk to Sara Monaco (@monaco_reviewcommons; Managing Editor) and Thomas Lemberger (@tlemberger; Deputy Head of Scientific Publications at EMBO and Project Leader for Review Commons). This episode was produced by Sónia Gomes Pereira and edited by Són…

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Peer Review Week LIVE Rapid Reviews with Stefano Bertozzi 34:51

1y ago34:51

34:51

To celebrate the end of Peer Review Week (2023) we recorded a live episode of the podcast with Stefano Bertozzi from Rapid Reviews to talk all things preprint peer review. No editing on this one!

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In the PI’s seat – Charlotte Odendall 49:57

1y ago49:57

49:57

This week we discuss the academic career of a young PI with Charlotte Odendall @codendall, a Sir Henry Dale Fellow at King’s College London. Join us for a conversation on starting a group with a Fellowship, how martial arts help with stress, and why we all need a friend who tells us “just do it”. Charlotte Odendall: https://www.kcl.ac.uk/research/o…

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Our 2 year birthday! The fascinating (and longer than you think) history of preprint servers with Matthew Cobb 1:01:43

1+ y ago1:01:43

1:01:43

It’s our 2 year birthday this month! To celebrate we take a trip back to the past and discuss the history of preprint servers with Matthew Cobb, a Professor at the University of Manchester. Find Matthew’s BBC podcast for more about the great science publishing scandal https://www.bbc.co.uk/programmes/m0004l7k If you want to learn more about the pre…

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Early Career Researcher Special 1:20:05

1+ y ago1:20:05

1:20:05

This week we discuss all things ECR with Mayank Chugh & Gracielle Higino, two current postdocs who are leading the efforts in fighting for a better environment for ECRs in academia. Gracielle is an ASAPbio fellow and program co-ordinator at BIOS2, a community of researchers who are exploring and applying modern-day computational and quantitative te…

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In the PI’s seat - Thibaut Brunet 45:23

1+ y ago45:23

45:23

This week we discuss the academic career of a young PI with Thibaut Brunet @thibaut_brunet, a G5 Group Leader at Institut Pasteur. Join us for a conversation on eating spiders, dancing creatures of the ocean, and the challenges of applying for and starting a group in the middle of the COVID-19 pandemic. Thibaut Brunet: https://research.pasteur.fr/e…

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Fibrosis; It's hot and it's cold 58:06

1+ y ago58:06

58:06

This week we discuss hot and cold fibrosis with Shoval Miyara, a PhD student at the Weizmann Institute of Science. Find shoval on Twitter (https://twitter.com/MiyaraShoval) Read the full preprint -> https://www.biorxiv.org/content/10.1101/2023.01.01.522422v1 This episode was produced by Jonny Coates and edited by Camila Valenzuela. If you enjoyed t…

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In the PI’s seat - Nicolás Rascovan 52:20

1+ y ago52:20

52:20

In the PI’s seat - Nicolás Rascovan This week we discuss the academic career of a young PI with Nicolás Rascovan @NRascovan, a G5 Group Leader at Institut Pasteur. Nicolás Rascovan: https://research.pasteur.fr/en/team/microbial-paleogenomics/ https://nicorascovan.wordpress.com/ This episode was hosted, produced, and edited by Dr. Camila Valenzuela.…

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Synthetic carbon fixation, lets save the world! 1:03:22

2y ago1:03:22

1:03:22

This week we discuss synthetic carbon fixation, running a lab as a postdoc and eLife’s new publishing model with Sebastian Wenk, a Postdoc at the Max Planck Institute of Molecular Plant Physiology. Read the full preprint -> https://www.biorxiv.org/content/10.1101/2022.09.28.509898v1.full Sebastian -> https://www.mpimp-golm.mpg.de/person/50878/21328…

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eLife: publishing, community and pushing the boundaries with Michael Eisen & Devang Mehta 1:29:08

2y ago1:29:08

1:29:08

This week we discuss the big changes occurring over at eLife with Editor in Chief Mike Eisen & original ECAG member Devang Mehta. From Jan 2023, eLife is focusing on public reviews and assessments of preprints and eliminating accept/reject decisions after peer review. Read more about this new model here: https://elifesciences.org/inside-elife/54d63…

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Xmas special - Battle of the servers, how to choose a preprint server 58:12

2y ago58:12

58:12

DISCLAIMER – These servers were reviewed from the approach of a first use instance and may not accurately reflect the full capabilities of each server. Moreover, any comments are opinions only. Preprint servers. There’s an incredibly interesting history behind them (watch this space for more on that next year) but as of 2022 there are over 50 diffe…

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RNA editing in squid; recoding the proteome with Kavita Rangan 44:44

2y ago44:44

44:44

This week we discuss RNA editing in cephalopods with postdoc Kavita Rangan. Read the full preprint -> https://www.biorxiv.org/content/10.1101/2022.09.25.509396v1.full This episode was produced by Jonny Coates and edited by Tala Noun & John Howard. If you enjoyed this show then hit that subscribe button and leave a review (on Apple Podcasts or Spoti…

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PreReview: leading the charge in transparent peer review of preprints with Daniela Saderi 44:08

2y ago44:08

44:08

This week we chat with Daniela Saderi, she is the Co-Founder and Director of PREreview (@prereview_), an open project with the mission to bring more equity and transparency to the evaluation of research content, giving systematically excluded researchers better ways to find, train, and contribute to peer review. In her role, she is responsible for …

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Colliding cells; how cell shape affects collision outcomes with Pedrom Zadeh 50:53

2y ago50:53

50:53

This week we discuss modeling cell-cell collisions with Pedrom Zadeh, a 4th year PhD student at Johns Hopkins University. We learn how to distill basic biology into models and just how important and useful modeling can be as a tool. Read the full preprint -> https://www.biorxiv.org/content/10.1101/2022.05.13.491710v1.full Twitter thread on the prep…

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Divide and Conquer: Cytoplasmic Divisions Without Nuclei 54:12

2y ago54:12

54:12

This week we discuss how cells can divide without nuclei and why this happens with Anand Bakshi, Fabio Echegaray Iturra (@fabioechegaray) & Mustafa G. Aydogan @AydoganLab. We also highlight Drosophila as an amazing model system that just keeps on giving and speak about the importance of preprints in collaboration and grant applications. We also dis…

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Mitochondrial DNA Sequencing and Diversity 43:59

2y ago43:59

43:59

This week we discuss mitochondrial DNA and its importance in aging with Amy Vandiver (@AmyVandiver2). We also highlight a new method to quickly sequence full length mitochondrial DNA allowing for mitochondrial genome comparisons and the understanding of the diversity between mitochondrial DNA. As usual we also discuss the process of pre-printing, p…

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Octopus and the many tentacles of research outputs 45:32

2y ago45:32

45:32

This week we discuss a different take on sharing scientific findings with Alex Freeman (@alex_freeman), creator of Octopus @science_octopus. Octopus is resetting the incentive structure for research sharing, putting the emphasis on assessing the quality of what people are doing within the lab. Find out more here https://www.jisc.ac.uk/rd/projects/o…

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Metabolic heterogeneity in macrophages 43:20

2y ago43:20

43:20

This week we discuss macrophage heterogeneity with Graham Heieis (@GrahamHeieis), a Post-doc at the Leiden University Medical Center (@LUMC_Leiden) in the Netherlands. We speak to him about mass cytometry and spectral flow cytometry and their use to investigate heterogeneity of tissue specific macrophages with regards to metabolism. We then have ou…

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Paper Retractions and Preprint Withdrawals with Michele Avissar-Whiting 44:23

2+ y ago44:23

44:23

We’ve gone full circle!! Join us this week as we talk to Michele Avissar-Whiting (@maw_tweets), one of our first ever guests on this podcast and Editor in Chief of Research Square, as we discuss what happens to a preprint when the downstream publication gets retracted, how the papers can be linked to the preprint and if the preprint should be withd…

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Ciliopathies, ‘Chlamy’ and Cilia length 39:45

2+ y ago39:45

39:45

This week we discuss cilia length, ciliopathies and Chlamydomonas reinhardtii (also known as ‘Chlamy’) with Brae Briggs (@BiggeBrae), a graduate student from at Dartmouth (@dartmouth),Geisel School of Medicine (@GeiselMed). We find out about a range of ciliopathies, the main composition of cilia as well as using ‘Chlamy’ as a model to study cilia l…

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Prachee Avasthi on ASAPbio, Arcadia Science and the open science mission on our one year birthday 1:44:24

2+ y ago1:44:24

1:44:24

We’re 1 year old today! And to help celebrate our Birthday we have an extra long conversation with the incomparable Prachee Avasthi (@PracheeAC), Associate Professor at Dartmouth, President of ASAPbio and CSO & co-founder of Arcadia Science). We discuss everything from Prachee’s career journey, role in promoting preprints and open science with ASAP…

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Can we regenerate the heart? 55:36

2+ y ago55:36

55:36

This week we discuss heart dedifferentiation and regeneration with Avraham Shakked @abingtonSA a final year PhD student, at the Weizmann Institute of Science, @WeizmannScience. We speak about their ingenious mouse model which uses transient and temporarily controlled ERBB2 expression which allows dedifferentiation and redifferentiation of cardiomyo…

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Episode 24: Baby hearts, inflammation and precarious postdocs 49:38

2+ y ago49:38

49:38

This week we discuss placental inflammation and heart development with postdoc Eleanor Jayne Ward and PI Suchita Nadkarni (@SciSuchita) from Queen Mary, University of London. In this preprint, the authors show that during embryonic heart development, neutrophils (innate immune cells) can sometimes cause placental inflammation. This inflammation lea…

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Episode 23: Tanycyting: Characterising a neural stem cell niche in the hypothalamus 55:29

2+ y ago55:29

55:29

This week we discuss a population of stem cells called tanycytes which line hypothalamus in the brain with Alex Moore (@alexthemessiah) an Operational Research Analyst in the Civil Service & Kavitha Chinnaiya a Post Doc from the University of Sheffield (@sheffielduni). Tanycytes are population of cells which line the 3rd ventricle in the hypothalam…

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Episode 22: Caloric Restriction: The Difference Sex and Age Can Make 57:18

2+ y ago57:18

57:18

CW:// This week's episode touches on some themes revolving around caloric restriction which some listeners may find difficult. This week we speak to Ben Thomas @BenThomasSci, a final year PhD student at the University of Edinburgh @EdinburghUni about the benefits of caloric restriction, the impact in male and female mice as well as the effect of ag…

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Episode 21: Science in motion: How journalists’ approach using preprints 53:27

2+ y ago53:27

53:27

This week we discuss how journalists approach using preprints with Alice Fleerackers (@FleerackersA), a PhD student at the Simon Fraser University (@SFU). She tells us how she went behind the scenes and to examine the decision making process of journalists on whether to use preprints or not, how they contextualized the science, and what practices t…

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Episode 20: Mini Brains - Organoids as 3D Brain Models 46:43

2+ y ago46:43

46:43

This week we discuss organoids and assembloids as models of neurodegenerative diseases with Sònia Sabaté Soler (@scisonias), a PhD student from the University of Luxembourg (@uni_lu). Find out about how 2D stem cells cultures are differentiated into complex 3D midbrain organoids which contain multiple cell types. We also discuss how microglia can b…

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Episode 19: John Inglis & Richard Sever on the Creation of BioRxiv 1:12:49

2+ y ago1:12:49

1:12:49

A really exciting special episode this week, as we talk to co-founders of BioRxiv (@biorxivpreprint) and MedRxiv (@medrxivpreprint) Richard Sever (@cshperspectives) & John Inglis (@JohnRInglis). We discuss how they met and started with BioRxiv along with the challenges they faced. We then chat about the considerations when accepting or rejecting pr…

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Episode 18: DNA Recorders 46:20

2+ y ago46:20

46:20

This week we discuss DNA recorders with Theresa Loveless (@TheresaLovele12), a Post Doc, at UC Irvine. DNA recorders can turn transient events into stable genomic ones and have been used to investigate cell fates and lineages. Join us as we find out more about how this is achieved and the incredible technology behind it!! We also chat about Theresa…

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Episode 17: On-demand Control of Endogenous Genes 42:49

2+ y ago42:49

42:49

This week we discuss an amazing new technique developed by Dr Jakub Gemperle (@GemperleJakub), a Marie Curie Postdoctoral Research Fellow at the University of Manchester (@OfficialUoM). This technique uses 3 different inducible systems to allow on-demand control of endogenous genes, including being able to remove genes and then re-express them. A n…

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Episode 16: The 7 Preprints of Christmas 50:51

3y ago50:51

50:51

This week is our Christmas Episode! In this episode the Preprints in Motion team get together and discuss exciting, new preprints with a festive theme. We talk about smart soil, mitochondria DNA in relation to COVID 19, shock absorber stress granules as well as a discussion on nepotistic journals and much more including festive cheer and merriment.…

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Episode 15 - The Exocyst: Somewhere between science and superstition 1:01:12

3y ago1:01:12

1:01:12

This week we discuss the exocyst with Dr Hannes Maib @hannes_maib a Post-Doctoral Researcher at the University of Dundee @dundeeuni!! He explains the complexities of the exocyst as well as the exciting biochemistry and binding assays used to understand its formation. In addition Hannes speaks candidly about starting working in a new lab as a Post-D…

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Episode 14: Be the change you want to see: Prefigurative politics in academia 43:07

3y ago43:07

43:07

This week we discuss prefigurative politics in academia with Stefano Davide Vianello, a PhD student at @EPFL_en in Switzerland. This is the idea that in order to change how a system works we should act in a way that reflects the change we want to see. In Stefano’s case: preprinting to be the end goal and he has therefore submitted a preprint withou…

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Episode 13 - Mice in Space: Characterizing Mouse Skeletal Muscles After 35-37 Days of Spaceflight 36:55

3y ago36:55

36:55

This week we discuss mice in space and the impact of prolonged space flight and how this can relate to austraunoughts with Jessica L Braun @jess_l_braun a PhD Student at the Brock University @BrockUniversity. Jessica speaks about her work looking at soleus and tibialis anterior muscles of mice which have spent 35-37 days on the international space …

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Episode 12 - Single Molecule Fingerprinting Reveals Different Amplification Properties of α-synuclein Oligomers 46:38

3y ago46:38

46:38

This week we discuss Parkinson’s Disease and single molecule spectroscopy with Dr Derrick Lau, a PostDoc at the University of New South Wales (@UNSW). Single molecular spectroscopy can be used to track the formation and purification of α-synuclein aggregates, a hallmark of PD, and potentially lead to a tool for early diagnosis of Parkinson’s Diseas…

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Episode 11 - Laterally Transferred Macrophage Mitochondria Act As A Signalling Source Promoting Cancer Cell Proliferation 46:51

3y ago46:51

46:51

This week we discussed the transfer of mitochondria from macrophages to cancer cells with Dr Chelsea Kidwill & Joseph Casalin, a Post-Doctoral Research Associate and PhD student at University of Utah (@UUtah) in the school of medicine. We delve into why this transfer occurs, the mechanism of transfer and how this impacts the recipient cells. We als…

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Episode 10 - Paywall The business of Scholarship 45:04

3y ago45:04

45:04

This week we discuss The Paywall Movie with Professor Jason Schmitt, chair of communication and Media at Clarkson University. We talk about academic publishing, the problems of the current system and more. In 2018, UK universities spent over £210 million on publication costs (access etc). This could have paid for; 700 ECR fellowships or 6500 postdo…

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Episode 09 - Incorrect Nucleotide Sequences Are Unacceptably Frequent Within Scientific Literature 47:41

3y ago47:41

47:41

This week we discuss how published nucleotide sequences are not always correct or to be trusted with Yasunori Park and Professor Jennifer A Byrne (@JAByrneSci), a research Assistant and PI at the University of Sydney (@Sydney_uni). We delve into the details of their nifty new text mining tool (Blast and Seek) which highlights papers with incorrect …

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Episode 08 - Identification of ACE2 modifiers by CRISPR screening 51:57

3y ago51:57

51:57

This week we discuss high throughput CRISPR/Cas9 screening and how these have been adapted to investigate novel treatments for COVID-19 with Emily Sherman a former Post Doc and Brian Emmer (@brianemmer), a new PI at University of Michigan (@UMIntMed) In this episode we cover details on how to conduct a high throughput CRISPR/Cas9 screen, the exciti…

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Episode 07 - A Transcriptional Switch Governs Fibroblast Activation in Heart Disease 36:26

3y ago36:26

36:26

This week we discuss BET inhibitors and fibroblast activation with Michael Alexanian @m_alexanian a Postdoctoral researcher at Gladstone Institutes @Gladstoneinst. Michael explains how BET inhibitors have emerged as a potent tool to reversibly interfere with enhancers to promoter signalling. This has been shown to ameliorate heart failure in mouse …

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Episode 06 - A Pretty Fly DNA Extraction Method 57:06

3+ y ago57:06

57:06

This week we discuss how to non-destructively extract and sequence DNA from historical mosquito and tsetse fly samples from the Natural History Museum’s collection. We discover a new method for doing just that with Dr Petra Korlevic (@petrathepostdoc), a Post-doctoral researcher at the EMBL-EBI (@emblebi)/Sanger Institute (@sangerinstitute), and Dr…

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Episode 05 - Pros and Cons of Preprints 1:14:00

3+ y ago1:14:00

1:14:00

It's all-change at Preprints in Motion this week! Host Jonny Coates takes on the role of guest, while Producer Emma Wilson and Editor John D Howard step in front of the mic for a change and co-host, to bring you a background discussion on the history, and pros and cons of Preprints. Analysis of changes between preprints and their published versions…

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Episode 04 - How Close Are We to Limb Regeneration? 41:27

3+ y ago41:27

41:27

This week we focus on limb regeneration in amphibians and ask how far away are we from mammalian regeneration? Maybe not as far as we think. We join Dr Can Aztekin @CanAztekin, a recent PhD graduate from Gurdon Institute @GurdonInstitute and current PI in EPFL, Switzerland @EPFL_en. We discuss regeneration in general and a novel tool to investigate…

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Episode 03 - Research Square EiC, Michele Avissar-Whiting 52:26

3+ y ago52:26

52:26

This week it’s something a little different! We chat with Dr Michele Avissar-Whiting (@maw_tweets) Editor in Chief of Research Square. Research Square is a Preprint platform which aims to make research communication publishing quicker, easier and fairer. We speak about their editing and reviewing process, open access journals as well as general Pre…

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Episode 02 - Meta-Research Citation needed? Wikipedia and the COVID-19 pandemic 58:32

3+ y ago58:32

58:32

Join us as we learn why referencing Wikipedia might not be such a bad idea. We speak to Omer Benjakob @omerbenj, Jonathan Sobel @JonathanSobel1 & Rona Aviram @rona_av who have been investigating the scientific backbone of Wikipedia pages and how referencing on Wikipedia has changed over the COVID-19 pandemic. We discuss how Wikipedia manages to rel…

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Episode 01 - How to build a microscope out of LEGO 39:29

3+ y ago39:29

39:29

This week join our host Jonny coates as he speaks with Dr Bart Vos, a research associate at the Munster University, as he reveals just how much he likes microscopes. Together they discuss how to build a high resolution LEGO microscope and how these can be used as useful teaching tools for kids and adults alike. They then delve in the world of acade…

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The trailer 0:57

3+ y ago0:57

0:57

Preprints in Motion is a shiny podcast diving into the fast paced world of preprinted science. Preprints have accelerated the speed at which scientific findings are shared and have helped to move academia towards a more equitable place. Join immunologist and open-science advocate Dr Jonny Coates as he talks to the early career researchers behind so…

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ポッドキャスト Preprints In Motion

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