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An audible review for board preparation for PM&R. Focused on basics of PM&R. The main source is Cuccurullo. Mostly for my own personal education. I spend a lot of time in a car and need to listen to help study. Support this podcast: https://podcasters.spotify.com/pod/show/steven-hansen6/support Hosted on Acast. See acast.com/privacy for more information.
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Brilliant Board Review & CME

Brilliant Board Review & CME

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🎙️ Brilliant Medicine: Your Internal Medicine Edge Stay sharp, stay current, and stay confident with Brilliant Medicine — the go-to podcast for Internal Medicine and Family Medicine physicians, residents, nurse practitioners, and physician assistants. Each episode delivers high-yield insights on the latest breakthroughs, practice-changing guidelines, and cutting-edge treatments in Internal Medicine — with just enough board review to keep your clinical reasoning razor-sharp. We cut through th ...
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Bradley's Micro Board Review

Jillian Bradley, Ph.D.

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月ごとの
 
On Bradley's Micro Board Review will cover one or two medical board relevant microorganisms each day. We will have board-style practice questions for those organisms and answer explanations. Join us for some quick micro fun! Support this podcast: https://podcasters.spotify.com/pod/show/bradleysmicroboardreview/support
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Peds in a Pod: A Pediatric Board Review

Candyce Mehler, DO & Taylor Millar, MD

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Are you a Pediatrician? Pediatrics Resident? Or maybe Family Medicine? Join us for Pediatric Board Review from your hosts Candyce Mehler, DO & Taylor Millar, MD. New episodes every quarter! Come spend some time enjoying board review....don’t believe us?! Give it a try :) Find us on twitter @pedsinapod or instagram @pedsinpodcast
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"The Today in Board Games Week in Review covers the latest in gaming. In each episode host Roger interviews one or more influential gamers, game publishers, designers, app developers, industry leaders, bloggers, podcasters, and/or videographers. We discuss the latest games (both new and upcoming), go in depth about hot Kickstarter projects, and talk trends, events, and predictions.
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Alison and Justin, review all their favourite board games, so you can be up to date on what’s hot in the world of tabletop games. Reviews of exciting games from Kickstarter and established games. Discover the features of board games from replay ability, how to win, component pieces, cost, expansions and the impact board games have on a marriage. Join them as they discuss whatever games they feel magnetised to.
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It’s Sunday Night and that means its board game date night! Seth and Jessie make time in their busy schedule to do something they love, hanging out together and playing board games. Listen in as they discuss board games, kids and marriage! Every few weeks they post a quick chat about the games they are playing and the wild and weird family they have. The episodes are kept short and offer an honest review on a game of the week. They love to focus on on co-op board games, family games and othe ...
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Your Redness Relief Eye Drops Are Lying to You. If I took your bottle of Visine away, it’s because I like you—and I want you to stop putting menthol-laced lies directly onto your corneas. Droopy Eyelid? Might Be Nothing. Might Be Neurology. One eyelid. One confusing pupil. Zero time to guess wrong. This one kept me thinking longer than it should’ve…
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Send us a text 🧠 Clinical Context Hydrochlorothiazide (HCTZ) vs. Chlorthalidone—a classic cardio debate! ALHAT once hinted at chlorthalidone’s superiority, but did a modern head-to-head trial confirm that? Let's break it down. 🧪 Study Snapshot: The HEADS-UP Trial Design: Randomized, head-to-head trial Population: ~14,000 patients, age ≥65, already …
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I dive into a mix of strange eye conditions, pop culture moments, and one very public showdown between a doctor and a group of anti-vaxxers on Jubilee’s Surrounded. But beyond the headlines, there’s a deeper conversation here—about what it costs to stay online, stay visible, and speak up. You’ll laugh, you’ll cringe, and you might even check your e…
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we ask a deceptively simple question: Would you let your kid become a doctor? What starts as a heartfelt reflection on medicine, sacrifice, and identity quickly unravels into a chaos-filled ride through policy disasters, parenting hypotheticals, and bone-based controversy. We touch on the NIH budget freeze and massive proposed Medicaid cuts—and why…
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we welcome back Dr. Kaveh Hoda—gastroenterologist, musician, podcaster, and accidental poop ambassador. We discuss what life is really like as a GI doc (spoiler: it’s not all about poop), how Match Day can go terribly wrong—or surprisingly right—and why some residents get influenced by... ultimate frisbee. Kaveh also opens up about his path into me…
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Send us a text 🧠 Clinical Context DOACs (Direct Oral Anticoagulants) have revolutionized anticoagulation—goodbye routine INRs, hello convenience. But while they’ve made our lives easier, they’re not always a fit for every scenario. Here's how to navigate the DOAC jungle. ✅ When DOACs Are Preferred Venous Thromboembolism (VTE) Atrial Fibrillation ⚠️…
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Send us a text 🧠 Clinical Context GLP-1 receptor agonists have taken center stage for both type 2 diabetes and obesity management, but their gastric side effects are giving anesthesiologists pause. The ASA's recent guidance recommends holding these agents before surgery to reduce risks of gastroparesis, regurgitation, and pulmonary aspiration. 🔬 AS…
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Send us a text 🧠 Clinical Context: You're prepping a patient for non-cardiac surgery—what's their cardiovascular risk? Turns out, it’s not always about echo reports or cath results. It starts with a stairs test (sort of). Duke Activity Status Index (DASI) and METs >4 can tell you if the heart's got enough reserve. 🚶‍♂️ “Can you walk up a flight of …
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Send us a text 🧠 Clinical Context Patients over 65 undergoing inpatient surgery face unique risks. Cognitive impairment, frailty, and increased vulnerability to delirium demand a proactive and nuanced approach to anesthesia and postoperative care. 🔍 Preoperative Priorities Age ≥65 and inpatient status should automatically trigger a frailty and cogn…
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Send us a text 🧠 Clinical Context: Episodic migraines (<15 days/month) that don’t respond to traditional preventives. Patients often fail beta blockers, AEDs, TCAs, CCBs — need new options. 🧪 Study – RCT on Atogepant: 315 patients, mostly women, who failed ≥2 oral preventives. Randomized to atogepant 60 mg daily vs placebo. Follow-up: 3 months. 📈 O…
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Send us a text 🧠 Historical practice: Pre-load clopidogrel (or ticagrelor) before cath. Rationale: reduce thrombotic burden prior to PCI. 🧪 New Data: Large observational study: 100k+ NSTEMI patients. No benefit in MI or death with pretreatment. Longer LOS, delayed CABG in pre-treated patients. 🧩 Clinical Takeaway: Defer P2Y12 until coronary anatomy…
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Send us a text 🧠 Clinical Context: Blood pressure errors due to bad positioning = misdiagnosis and mistreatment. We often blame the drug, when the data was flawed to begin with. 🧪 Study Highlights: 104 patients tested with 3 positions: Hand in lap: BP falsely elevated by 4 mmHg. Arm unsupported: +6 mmHg (most common real-world scenario). Arm suppor…
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Send us a text 🧠 Clinical Tool: Spot urine sodium 2 hours after IV loop diuretic. If <50–70 mmol/L → inadequate response. Consider doubling dose or switching loop agents. 💡 Tips: Also assess urine output in first 6 hours (<100–150 mL/hr = poor response). Less helpful after 24 hrs or in chronic diuretic users. 🧩 Clinical Takeaway: Fast, practical gu…
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Send us a text 🧪 VOYAGER-PAD Trial: Patients with PAD post lower extremity revascularization. Rivaroxaban 2.5 mg BID + aspirin vs aspirin alone. 📈 Results: ↓ Major Adverse CV Events (MACE). ↓ Major Adverse Limb Events (MALE). Modest ↑ in bleeding — no ↑ in fatal bleeds. 🧩 Clinical Takeaway: Now guideline-endorsed for symptomatic PAD post-interventi…
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Send us a text 🧠 Clinical Context We’ve long been taught to stop metformin once GFR drops below 30 due to concerns about lactic acidosis. But what if—just maybe—some patients might actually do better by continuing it? Enter a large-scale Scottish national database review that turned this dogma on its head. 🧪 Study Highlights Design: Retrospective a…
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Send us a text 🧠 Clinical Context Fever is known to be associated with worse neurologic outcomes in stroke, both ischemic and hemorrhagic. Intuitively, preventing fever seems like a slam-dunk goal, right? This study took that theory to trial, literally. 🧪 Study Highlights: The INTREPID Trial Design: Open-label, randomized controlled trial with blin…
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Send us a text 🧠 Core Concept: Cerebral perfusion pressure (CPP) = MAP – ICP. Normal ICP = ~10 mmHg; threshold for concern >20 mmHg. 🧰 Management Strategies: Elevate head of bed (30°), ensure neck is midline. 3% hypertonic saline preferred over mannitol in AKI. Short-term hyperventilation (↓ PaCO₂ → vasoconstriction). Consider sedation or decompres…
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Send us a text 🧠 Clinical Problem: Behavioral disturbances in Alzheimer’s are notoriously hard to treat. Guidelines tell us: “Don’t use antipsychotics” — but what do you do at 2AM when Nana's throwing punches? 💊 Study Overview: 345 patients, moderate-severe Alzheimer’s + aggressive agitation. Brexpiprazole 2–3 mg daily vs placebo. Dosing didn’t dif…
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Send us a text 🧠 Hidden epidemic: 50–70% of premenopausal women have iron deficiency. Also common in CKD, GI bleeding, chronic disease. 🔍 Diagnosis Pearls: Ferritin cutoff: <30 ng/mL (not 20!) for iron deficiency. RLS patients: target ferritin >75. Consider retic count: low = underproduction; high = bleeding/hemolysis. 💊 Treatment Tips: Oral iron: …
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Send us a text 🧪 Study: TXA within 2 hrs of ICH did not reduce hematoma expansion. No benefit in functional outcome or mortality. ⚠️ Note: Slight ↑ in thromboembolic events (3% vs 1%). 🧩 Clinical Takeaway: No routine use for TXA in spontaneous ICH. Still potential niche use in select trauma cases. Please visit www.Brilliantcourses.com to reflect on…
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Send us a text 🧠 Study: Compared transfusion thresholds of Hgb <8 vs <10 in subarachnoid hemorrhage. 📊 Findings: No difference in modified Rankin Score at 12 months. Fewer transfusions, fewer complications in <8 group. 🧩 Clinical Takeaway: Restrictive transfusion strategy is safe in neuro ICU. Less exposure = better outcomes. Please visit www.Brill…
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Send us a text 🧠 Problem: RLS causes chronic sleep disruption, often worsens in hospital or peri-op settings. 💊 Management: First-line: Gabapentin or Pregabalin (per American Academy of Sleep Medicine). Avoid long-term dopamine agonists — cause augmentation and impulse control disorders. 🩸 Bonus Tip: Check ferritin — keep it >75 ng/mL. Oral or IV i…
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Send us a text 🧠 Problem: 80% of menopausal women suffer from vasomotor symptoms (hot flashes, night sweats). Many can't take hormone therapy (VTE, CAD, breast CA). 💊 Fezolinetant: NK3 receptor antagonist — first in class. Reduces frequency and intensity of hot flashes. Safe in patients who can’t take estrogen. ⚠️ Side Effects: GI symptoms, transam…
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Send us a text 🧠 Clinical Myth: “Delay levodopa to delay motor complications.” 🧪 LEAP Trial (Levodopa in Early Parkinson’s): Compared early start vs 40-week delayed start. 5-year follow-up showed no difference in motor fluctuations or dyskinesia. 📈 Key Outcomes: Early levodopa = better function earlier, no long-term harm. Wearing off effect was sim…
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Send us a text 🧠 Clinical Question: Are we overtreating bloodstream infections with 14-day regimens? 🧪 Study Overview: Multicenter RCT in ICU/inpatient settings (7 vs 14 days of antibiotics). Excluded: Immunosuppressed, endocarditis, Staph aureus, and infections needing longer therapy. 📈 Findings: No difference in 90-day mortality or relapse. More …
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Send us a text 🧪 Study: Retrospective look at patients with intracranial hemorrhage (ICH) on warfarin for mechanical valves. Followed for stroke, rebleed, mortality. 📈 Findings: Only 2 strokes in first 7 days after stopping warfarin. Most resumed warfarin around day 7 with low rebleed risk. ⚠️ Exclusions: Massive bleeds, unstable patients, large he…
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Send us a text 💊 Study: SURMOUNT-HF trial — patients with obesity and HFpEF. Tirzepatide = ↓ HF hospitalizations and ↑ quality of life. 📈 Benefits: Significant weight loss. Better metabolic profiles. GI side effects: ~6% (nausea, diarrhea). 🧩 Clinical Takeaway: A major contender for cardio-metabolic syndrome with HFpEF. More than just a diabetes or…
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Send us a text 🧠 Background: RSV causes significant morbidity/mortality in older adults. Previously considered a pediatric virus only. 📈 Epidemiology: Hospitalization rate: 91/100,000 (ages 64–74). 738/100,000 in assisted living patients. 💉 Vaccine Update: CDC now recommends RSV vaccine for: All ≥75 years old. 60–74 years with chronic conditions (l…
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Send us a text 📊 What It Is: A modern CV risk estimator developed from 2.3 million-person dataset. Replaces outdated ASCVD calculator (based on 25k). 🧠 Features: Adds BMI, GFR, A1C, and zip code. Omits race — more equitable. Outputs risk of heart disease, stroke, heart failure. ⚠️ Caveats: Generally gives lower risk estimates vs ASCVD. May reduce s…
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Send us a text 🧠 Context: Rising rates of carbapenem-resistant gram-negatives, especially those producing MBLs like NDM, VIM. 💊 Drug Combo: Aztreonam + Avibactam = a lifeline for metallo-beta-lactamase (MBL) producers. FDA-approved for: Complicated intra-abdominal infections (with metronidazole). Hospital-acquired and ventilator-associated pneumoni…
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Send us a text 🧪 Key Insights: Observational data links semaglutide (GLP-1 RA) to increased risk of non-arteritic anterior ischemic optic neuropathy (NAION). Incidence: ~9–15 cases per 100,000 patient-years. Possible mechanism: GLP-1 receptors in optic nerve ganglion cells. No proven causality yet — retrospective study only. 🧩 Clinical Takeaway: Ri…
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Send us a text 🧠 Clinical Context: Hypertrophic obstructive cardiomyopathy (HOCM): Genetic disorder causing LVOT obstruction. Traditionally managed with BBs, CCBs, disopyramide… or surgery. 💊 Drug: Mavacamten (Cardiac Myosin Inhibitor) Targets sarcomeric hypercontractility directly. FDA approved for NYHA Class II–III obstructive HCM. 🧪 EXPLORER-HCM…
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Send us a text 🧠 Clinical Context: For patients who absolutely cannot tolerate statins — despite trying multiple options or experiencing severe side effects. Reminder: Always try multiple statins first (different types, dosages, timing) before declaring “statin intolerance.” 💊 What is Bempedoic Acid? Non-statin oral agent, works upstream of HMG-CoA…
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Send us a text 🧠 Trial: DOAC started at 3 days vs 8–14 days post-stroke in AF patients. 📊 Results: No ↑ bleeding. No ↑ ischemic events. 🧩 Clinical Takeaway: Safe to start within 4 days in mild to moderate stroke. Still tailor based on infarct size and bleeding risk. Please visit www.Brilliantcourses.com to reflect on this activity with Learner+ pla…
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Send us a text 🧪 Trials: RESHAPE-HF2: ↓ HF hospitalizations with transcatheter edge-to-edge repair vs medical therapy. MATTR: Transcatheter approach non-inferior to surgical repair. 🧩 Clinical Takeaway: Game-changing for patients too high risk for surgery. Less peri-op risk, faster recovery — mitral repair is heading the way of TAVR. Please visit w…
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Send us a text 🧪 Key Findings: Cohort study: SGLT2 inhibitors led to significantly lower rates of nephrolithiasis compared to GLP-1 RAs. Mechanism: increased urinary flow and uric acid excretion. 🔢 Stats: NNT = 20 for prevention. NNT = 5 for recurrent stone formers. 🧩 Clinical Takeaway: Another bonus benefit of SGLT2 inhibitors. May sway decision i…
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Send us a text 🧪 The EPOC Trial: Compared FLOT chemotherapy alone vs chemo + radiation before surgery in localized esophageal/gastroesophageal adenocarcinoma. 📈 Findings: FLOT alone led to better 3-year progression-free survival: 51.6% vs 35%. No survival benefit from adding radiation. Patients receiving FLOT alone had fewer complications, improved…
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Send us a text 🧠 Clinical Context: Nursing home residents are fragile fall-prone patients. Starting a new antihypertensive could trigger orthostasis → serious fractures. 🧪 Study – VA Nursing Home Cohort: 13,000+ residents tracked from 2006–2019, mean age ~78. Examined fracture risk 30 days after starting an antihypertensive. Fractures studied: Pelv…
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Send us a text 🧠 Clinical Context: Historically, breast cancer treatment has included radical mastectomies and full axillary dissections. New data supports less invasive approaches for specific low-risk populations. 🧪 The SOUND Trial (and similar studies): T1–T2 tumors (≤5 cm), clinically node-negative, ER+. Compared no axillary surgery vs sentinel…
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Send us a text 🧠 Clinical Context: Subclinical atrial fibrillation = asymptomatic episodes of AF detected by implantable monitors or Holters, lasting 6 minutes to 24 hours. Big Question: Should we anticoagulate these patients? 🧪 Study Highlights – ARTESiA Trial: Design: 4,012 patients (mean age 76.8), randomized to apixaban 5 mg BID vs ASA 81 mg da…
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Send us a text 🧠 Clinical Problem: HFpEF (Heart Failure with Preserved EF) has lacked effective, proven therapies. Finerenone (non-steroidal MRA) offers new hope. 🧪 FINEARTS-HF Trial: 6,000+ patients with EF ≥40%, followed for ~32 months. Compared Finerenone vs placebo. 📈 Results: ↓ Heart failure hospitalization significantly. No significant reduct…
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Send us a text 🧠 Clinical Context: BBs have been MI standard since the thrombolysis era. But do they still help when patients get PCI, statins, and ACEs? 🧪 Two Major Studies: Swedish Registry Study: Post-MI patients with preserved EF. All received PCI + standard meds. BB vs no BB: No difference in death or recurrent MI. French Study (New England Jo…
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Send us a text 🧠 Clinical Problem: HFpEF (Heart Failure with Preserved EF) has lacked effective, proven therapies. Finerenone (non-steroidal MRA) offers new hope. 🧪 FINEARTS-HF Trial: 6,000+ patients with EF ≥40%, followed for ~32 months. Compared Finerenone vs placebo. 📈 Results: ↓ Heart failure hospitalization significantly. No significant reduct…
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Send us a text 🧠 Surprising contender: OA is not just wear-and-tear — there's an inflammatory phenotype. 🧪 Trial: MTX 10–25 mg/week in knee OA with persistent pain. Significant ↓ pain and improved function vs placebo. ⚠️ Side Effects: GI upset, mouth ulcers, fatigue. Hepatotoxicity, myelosuppression, pulmonary fibrosis (rare). Always co-prescribe f…
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Send us a text 🧠 Clinical Question: What's the optimal hemoglobin threshold for transfusion post-MI? Old dogma: “Keep Hgb >10”. New data: Less might be just as safe. 🧪 The MINT Trial (Myocardial Ischemia & Transfusion): Compared liberal (Hgb <10) vs restrictive (Hgb <8) transfusion strategies. Lower 30-day recurrent MI or cardiac death seen with Hg…
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Send us a text 🧠 Clinical Context Heart failure with preserved ejection fraction (HFpEF) typically presents with orthopnea, dyspnea, edema, and often subtle signs like an S3 or elevated JVP—despite a normal EF (>50%). Diagnosing it requires nuance, and ruling out other causes of dyspnea is key. 🧪 Rule Out First Before calling it HFpEF, think differ…
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Send us a text 🧪 Study: Vitamin K2 (180 mcg) reduced nocturnal leg cramps in elderly. 📉 Results: Cramps/week ↓ from 3.6 → ~1 over 8 weeks. Safe and well-tolerated. 🧩 Clinical Takeaway: Consider a K2 trial in patients with chronic cramps — especially if sleep-disrupting. Avoid in patients on warfarin. Please visit www.Brilliantcourses.com to reflect…
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Send us a text 🧠 Clinical Background: Inflammation plays a big role in atherothrombosis. Colchicine — an old gout drug — shows promise in CV risk reduction. 🧪 COLCOT Trial: Colchicine 0.5 mg daily post-MI. Greatest benefit in patients with type 2 diabetes. 📈 Outcomes: Reduced MACE (MI, stroke, death) in diabetics. Adverse Effects: Nausea, diarrhea,…
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Send us a text 🧪 Study: Patients ≥55 with no relapses in 5 yrs and no new lesions in 3 yrs may stop disease-modifying therapy (DMT). No significant difference in disability progression. 🧩 Clinical Takeaway: De-escalation strategy in stable MS may reduce cost and side effects. Still requires close neurology follow-up. Please visit www.Brilliantcours…
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I share one of the more difficult days in the OR—when a routine cataract surgery didn’t go according to plan. I walk through the moment everything shifted, how I kept my cool, and what came after—both technically and emotionally. If you’ve ever wondered what it feels like to be a surgeon in that moment, this episode is a rare, honest window into it…
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