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#147 - Hussein Yassine, M.D.: Deep dive into the “Alzheimer’s gene” (APOE), brain health, and omega-3s
Manage episode 283712851 series 2352826
We discuss:
- Hussein’s Background and introduction to brain composition (3:00);
- The blood-brain barrier and brain filtration (8:00);
- Lipids and brain function (13:00);
- How the brain utilizes energy (18:00);
- Apolipoprotein E (ApoE) structure and function in the periphery (27:30);
- ApoE function in the brain (38:15);
- Evolutionary origins of ApoE isoforms (43:45);
- ApoE4 variant and Alzheimer’s disease (AD) risk (53:30);
- Dietary fuel preference with the ApoE4 allele (1:03:00);
- The role of omega-3 fatty acids in the brain (1:13:30);
- Comparing findings from the REDUCE-IT and STRENGTH trial (1:21:45):
- The relationship between dietary omega-3 intake and brain health (1:34:15);
- Preventing cognitive decline: A critical window for DHA in ApoE4 carriers? (1:42:30);
- Hussein’s ongoing research and recommendations for E4 carriers (1:54:00); and
- More.
Learn more: https://peterattiamd.com/ Show notes page for this episode: https://peterattiamd.com/HusseinYassine Subscribe to receive exclusive subscriber-only content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Connect with Peter on Facebook | Twitter | Instagram.
348 つのエピソード
Manage episode 283712851 series 2352826
We discuss:
- Hussein’s Background and introduction to brain composition (3:00);
- The blood-brain barrier and brain filtration (8:00);
- Lipids and brain function (13:00);
- How the brain utilizes energy (18:00);
- Apolipoprotein E (ApoE) structure and function in the periphery (27:30);
- ApoE function in the brain (38:15);
- Evolutionary origins of ApoE isoforms (43:45);
- ApoE4 variant and Alzheimer’s disease (AD) risk (53:30);
- Dietary fuel preference with the ApoE4 allele (1:03:00);
- The role of omega-3 fatty acids in the brain (1:13:30);
- Comparing findings from the REDUCE-IT and STRENGTH trial (1:21:45):
- The relationship between dietary omega-3 intake and brain health (1:34:15);
- Preventing cognitive decline: A critical window for DHA in ApoE4 carriers? (1:42:30);
- Hussein’s ongoing research and recommendations for E4 carriers (1:54:00); and
- More.
Learn more: https://peterattiamd.com/ Show notes page for this episode: https://peterattiamd.com/HusseinYassine Subscribe to receive exclusive subscriber-only content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Connect with Peter on Facebook | Twitter | Instagram.
348 つのエピソード
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