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Cell Therapy Manufacture: How to scale the manufacture of living drugs

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Manage episode 333590390 series 2994360
コンテンツは TTP plc によって提供されます。エピソード、グラフィック、ポッドキャストの説明を含むすべてのポッドキャスト コンテンツは、TTP plc またはそのポッドキャスト プラットフォーム パートナーによって直接アップロードされ、提供されます。誰かがあなたの著作権で保護された作品をあなたの許可なく使用していると思われる場合は、ここで概説されているプロセスに従うことができますhttps://ja.player.fm/legal

Following our first episode of two focusing on cell and gene therapies, outlining the promise and practicalities of delivering curative therapies for chronic diseases, we now focus on cell therapies - so called ‘living drugs’ that are both as powerful as they are complex. Despite the impressive trials and life-changing impacts at the individual level, it’s still not possible to manufacture cell therapies at scales that could benefit a wider range of patients. So what are the differences between cell therapies and conventional medicines that make them so difficult to manufacture? Can we redeploy hardware and learnings from other industries or are custom solutions needed? And does the ‘where’ we manufacture these therapies matter more than the ‘how’? As we discover in this episode, efforts to address these questions and provide scalable manufacturing solutions could unleash a new wave of pharmaceutical innovation that promises to revolutionise the way we develop medicines.

Find out more on this week's episode of Invent: Life Sciences from TTP.

This Week's Guests

Dr. Edwin Stone

Ed is our head of cell and gene at TTP. After a PHD specialising in Vehicle Dynamics from the University of Cambridge, Ed started working at TTP some 18 years ago, most of which has been spent specialising in cell and gene. He’s been focusing on the manufacturing realm of cell and gene for the past seven years. His work spans everything from commercial strategy through to technology development and on to production.

https://www.linkedin.com/in/edwin-stone-98560212/

Mike Lehmicke
Mike is the Senior Director of Science and Industry Affairs at the Alliance for Regenerative Medicine, and has over 20 years of R&D experience in biomaterials, medical devices, and regenerative medicine. His work focuses on cell based tissue engineering, bioceramics and medicines which have the ability to help repair or replace damaged human cells or tissues.
https://www.linkedin.com/in/michael-lehmicke-76b45435/

Dr. Félix A. Montero-Julian
Félix is a Scientific Director of the Healthcare Business of bioMérieux. With over 25 years of experience in industrial and clinical diagnostics, Félix is extensively involved in the implementation and acceptance of rapid and alternative microbiological methods, with an array of technical experience across the cell and gene therapy manufacturing process.
https://www.linkedin.com/in/f%C3%A9lix-a-montero-julian-phd-0a3a501b/

The Technology Partnership is where scientists & engineers develop new products & technologies that bring innovation & value to clients.
Find out more about our work here: https://www.ttp.com/

  continue reading

20 つのエピソード

Artwork
iconシェア
 
Manage episode 333590390 series 2994360
コンテンツは TTP plc によって提供されます。エピソード、グラフィック、ポッドキャストの説明を含むすべてのポッドキャスト コンテンツは、TTP plc またはそのポッドキャスト プラットフォーム パートナーによって直接アップロードされ、提供されます。誰かがあなたの著作権で保護された作品をあなたの許可なく使用していると思われる場合は、ここで概説されているプロセスに従うことができますhttps://ja.player.fm/legal

Following our first episode of two focusing on cell and gene therapies, outlining the promise and practicalities of delivering curative therapies for chronic diseases, we now focus on cell therapies - so called ‘living drugs’ that are both as powerful as they are complex. Despite the impressive trials and life-changing impacts at the individual level, it’s still not possible to manufacture cell therapies at scales that could benefit a wider range of patients. So what are the differences between cell therapies and conventional medicines that make them so difficult to manufacture? Can we redeploy hardware and learnings from other industries or are custom solutions needed? And does the ‘where’ we manufacture these therapies matter more than the ‘how’? As we discover in this episode, efforts to address these questions and provide scalable manufacturing solutions could unleash a new wave of pharmaceutical innovation that promises to revolutionise the way we develop medicines.

Find out more on this week's episode of Invent: Life Sciences from TTP.

This Week's Guests

Dr. Edwin Stone

Ed is our head of cell and gene at TTP. After a PHD specialising in Vehicle Dynamics from the University of Cambridge, Ed started working at TTP some 18 years ago, most of which has been spent specialising in cell and gene. He’s been focusing on the manufacturing realm of cell and gene for the past seven years. His work spans everything from commercial strategy through to technology development and on to production.

https://www.linkedin.com/in/edwin-stone-98560212/

Mike Lehmicke
Mike is the Senior Director of Science and Industry Affairs at the Alliance for Regenerative Medicine, and has over 20 years of R&D experience in biomaterials, medical devices, and regenerative medicine. His work focuses on cell based tissue engineering, bioceramics and medicines which have the ability to help repair or replace damaged human cells or tissues.
https://www.linkedin.com/in/michael-lehmicke-76b45435/

Dr. Félix A. Montero-Julian
Félix is a Scientific Director of the Healthcare Business of bioMérieux. With over 25 years of experience in industrial and clinical diagnostics, Félix is extensively involved in the implementation and acceptance of rapid and alternative microbiological methods, with an array of technical experience across the cell and gene therapy manufacturing process.
https://www.linkedin.com/in/f%C3%A9lix-a-montero-julian-phd-0a3a501b/

The Technology Partnership is where scientists & engineers develop new products & technologies that bring innovation & value to clients.
Find out more about our work here: https://www.ttp.com/

  continue reading

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