Gordan Lauc PhD: Glycans- The Next Biological Longevity Clock?

Health Longevity Secrets

#011-Glycans are being hailed as possibly the next great biological longevity clock. Today we speak with the leading expert on the subject.
Gordan Lauc PhD, is Professor of Biochemistry and Molecular biology at the University of Zagreb and Co-Founder and Chief Scientific Officer at GlycanAge. He graduated from the University of Zagreb Faculty of Science in 1992, and obtained PhD in Biochemistry and the University of Zagreb.

Take home points:

Glycans– the third revolution in evolution

Nuclei acids - 4 building blocks [linear]
Proteins - 20 amino acids [linear]
Glycoproteins- 2000+ [nonlinear]

Examples -Blood groups ABO are glycans

Post translational-make protein

Glycans modifications of proteins lipids and even DNA by sugar

Nonlinear branching oligosaccharide

Glucose-monosaccharide-

Post translational modifications-

Phosphorylation

Glycosylation

AGE- advanced glycation end products——reaction glucose and proteins- not the same as glycosylation.

Immunoglobulins- older get more pro inflammatory glycans-

Igg glycosylation suppress inflammation

Human glycan project

Health Longevity Secrets show listeners who wish to try The Glyconage longevity clock on themselves can receive a 20% discount enter the code ROBERTLUFKIN at the glycanage.com website.

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We do work with sponsors and brands. If you are interested in working with us for your health industry product or service, please contact us at: https://www.robertlufkinmd.com/contact/
NOTE: This is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have. Never disregard professional medical advice or delay in seeking it becaus...